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An explosion at a Dow Chemical plant in northeastern Massachusetts Thursday critically injured four people and damaged the building.

Firefighters, paramedics and police responded to the plant in North Andover, MA, at 2:30 p.m. Thursday.

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Four people with shrapnel and burn injuries ended up rushed to the hospital in critical condition, said officials at Lawrence General Hospital. Three of the victims later transferred to hospitals in Boston.

North Andover Town Manager Andrew Maylor said no chemicals released into the air and there is no danger to the surrounding area.

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The cause of the blast is under investigation. Local, state and federal authorities are at the scene. A worker died in a chemical explosion at the same plant in 2013.

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